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  <xsd:element name="CommonStockCapitalSharesReservedForFutureIssuanceStockIncentivePlan" id="aeon_CommonStockCapitalSharesReservedForFutureIssuanceStockIncentivePlan" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" />
  <xsd:element name="CommonStockCapitalSharesReservedForFutureIssuanceWarrants" id="aeon_CommonStockCapitalSharesReservedForFutureIssuanceWarrants" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" />
  <xsd:element name="CommonStockCapitalSharesReservedForFutureIssuanceContingentConsideration" id="aeon_CommonStockCapitalSharesReservedForFutureIssuanceContingentConsideration" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" />
  <xsd:element name="CommonStockCapitalSharesReservedForFutureIssuanceConvertibleDebtSecurities" id="aeon_CommonStockCapitalSharesReservedForFutureIssuanceConvertibleDebtSecurities" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" />
  <xsd:element name="SeriesaWarrantsMember" id="aeon_SeriesaWarrantsMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="SeriesBWarrantsMember" id="aeon_SeriesBWarrantsMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="SeriesaAndBWarrantsMember" id="aeon_SeriesaAndBWarrantsMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="PublicOfferingDisclosureAbstract" id="aeon_PublicOfferingDisclosureAbstract" type="xbrli:stringItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="PublicOfferingDisclosureTextBlock" id="aeon_PublicOfferingDisclosureTextBlock" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="SeriesWarrantsMember" id="aeon_SeriesWarrantsMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="NumberOfCommonUnitsIssuedDuringPeriod" id="aeon_NumberOfCommonUnitsIssuedDuringPeriod" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="NumberOfCommonSharesIssuablePerCommonUnit" id="aeon_NumberOfCommonSharesIssuablePerCommonUnit" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" />
  <xsd:element name="NumberOfWarrantsIssuablePerCommonUnit" id="aeon_NumberOfWarrantsIssuablePerCommonUnit" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" />
  <xsd:element name="NumberOfDaysOptionToPurchaseAdditionalShares" id="aeon_NumberOfDaysOptionToPurchaseAdditionalShares" type="xbrli:durationItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="MaximumPercentageOfCommonSharesToBePurchasedInOption" id="aeon_MaximumPercentageOfCommonSharesToBePurchasedInOption" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="PurchasePriceOfAdditionalWarrant" id="aeon_PurchasePriceOfAdditionalWarrant" type="dtr-types:perShareItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="ClassOfWarrantOrRightNumberOfWarrantsExercised" id="aeon_ClassOfWarrantOrRightNumberOfWarrantsExercised" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="FloorPriceOfWarrantsBeforeStockholderApprovalDate" id="aeon_FloorPriceOfWarrantsBeforeStockholderApprovalDate" type="dtr-types:perShareItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" />
  <xsd:element name="FloorPriceOfWarrantsAfterStockholderApprovalDate" id="aeon_FloorPriceOfWarrantsAfterStockholderApprovalDate" type="dtr-types:perShareItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" />
  <xsd:element name="WarrantsAndRightsGrantDateFairValue" id="aeon_WarrantsAndRightsGrantDateFairValue" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="credit" />
  <xsd:element name="WarrantsMultiplierFactor" id="aeon_WarrantsMultiplierFactor" type="xbrli:pureItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" />
  <xsd:element name="EmploymentInducementIncentiveAward2025PlanMember" id="aeon_EmploymentInducementIncentiveAward2025PlanMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="ShareBasedPaymentArrangementEarnoutVestingExpense" id="aeon_ShareBasedPaymentArrangementEarnoutVestingExpense" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="PublicOfferingMember" id="aeon_PublicOfferingMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="NumberOfFounderSharesSubjectToVestingForfeited" id="aeon_NumberOfFounderSharesSubjectToVestingForfeited" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="LitigationSettlementCash" id="aeon_LitigationSettlementCash" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="credit" />
  <xsd:element name="LitigationSettlementShare" id="aeon_LitigationSettlementShare" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="credit" />
  <xsd:element name="LitigationSettlementWarrantsIssued" id="aeon_LitigationSettlementWarrantsIssued" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" />
  <xsd:element name="CommonStockCapitalSharesReservedForFutureIssuanceStockIncentivePlanAndEmployeeStockPurchasePlan" id="aeon_CommonStockCapitalSharesReservedForFutureIssuanceStockIncentivePlanAndEmployeeStockPurchasePlan" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" />
  <xsd:element name="PreFundedWarrantsMember" id="aeon_PreFundedWarrantsMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="NumberOfReportableSegmentsNotDisclosedFlag" id="aeon_NumberOfReportableSegmentsNotDisclosedFlag" type="xbrli:booleanItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="PipeWarrantsMember" id="aeon_PipeWarrantsMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="ConvertibleNotesMaturingOnMarch2027Member" id="aeon_ConvertibleNotesMaturingOnMarch2027Member" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="ConvertibleNotesMaturingOnApril2027Member" id="aeon_ConvertibleNotesMaturingOnApril2027Member" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="ExchangeAgreementMember" id="aeon_ExchangeAgreementMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="DebtInstrumentConvertibleBeneficialOwnershipLimitationPercentage" id="aeon_DebtInstrumentConvertibleBeneficialOwnershipLimitationPercentage" type="dtr-types:percentItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="NewConvertibleNoteIssuedInLieOfExchangeMember" id="aeon_NewConvertibleNoteIssuedInLieOfExchangeMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="DaewongWarrantMember" id="aeon_DaewongWarrantMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="ReclassificationOfDerivativeLiabilityToEquityAndWarrantLiabilities" id="aeon_ReclassificationOfDerivativeLiabilityToEquityAndWarrantLiabilities" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="PayablesForSuppliesAndAnalyticalTestingCurrent" id="aeon_PayablesForSuppliesAndAnalyticalTestingCurrent" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="credit" />
  <xsd:element name="AccruedSellingGeneralAndAdministrativeConsultingExpensesCurrent" id="aeon_AccruedSellingGeneralAndAdministrativeConsultingExpensesCurrent" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="credit" />
  <xsd:element name="AccruedResearchAndDevelopmentConsultingExpensesCurrent" id="aeon_AccruedResearchAndDevelopmentConsultingExpensesCurrent" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="credit" />
  <xsd:element name="LegalFeesOutstanding" id="aeon_LegalFeesOutstanding" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" xbrli:balance="credit" />
  <xsd:element name="PreFundedWarrantMember" id="aeon_PreFundedWarrantMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="PipeWarrantsAndDaewoongWarrantsMember" id="aeon_PipeWarrantsAndDaewoongWarrantsMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="PrivatePlacementAbstract" id="aeon_PrivatePlacementAbstract" type="xbrli:stringItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="PrivatePlacementTextBlock" id="aeon_PrivatePlacementTextBlock" type="dtr-types:textBlockItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="PipePreFundedWarrantsMember" id="aeon_PipePreFundedWarrantsMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="TrueUpWarrantsMember" id="aeon_TrueUpWarrantsMember" type="dtr-types:domainItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="true" />
  <xsd:element name="PricePerWarrantIssued" id="aeon_PricePerWarrantIssued" type="dtr-types:perShareItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" />
  <xsd:element name="StockTransactionInvestorProtectionPeriod" id="aeon_StockTransactionInvestorProtectionPeriod" type="xbrli:durationItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="UnrealizedGainLossOnInitialRecognitionOfDerivatives" id="aeon_UnrealizedGainLossOnInitialRecognitionOfDerivatives" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="credit" />
  <xsd:element name="ShareConversionRatio" id="aeon_ShareConversionRatio" type="xbrli:pureItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="MaximumContingentConsiderationSharesIssuable" id="aeon_MaximumContingentConsiderationSharesIssuable" type="xbrli:sharesItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="MinimumFloorPriceForExercisingWarrants" id="aeon_MinimumFloorPriceForExercisingWarrants" type="dtr-types:perShareItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="instant" abstract="false" />
  <xsd:element name="QualifiedFinancingMinimumProceedsThreshold" id="aeon_QualifiedFinancingMinimumProceedsThreshold" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
  <xsd:element name="WrittenOnNoticePeriodForThirdParty" id="aeon_WrittenOnNoticePeriodForThirdParty" type="xbrli:durationItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="ConversionPriceLookBackPeriodTradingDays" id="aeon_ConversionPriceLookBackPeriodTradingDays" type="xbrli:durationItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" />
  <xsd:element name="ProceedsFromPipeFinancing" id="aeon_ProceedsFromPipeFinancing" type="xbrli:monetaryItemType" substitutionGroup="xbrli:item" nillable="true" xbrli:periodType="duration" abstract="false" xbrli:balance="debit" />
</xsd:schema>
